TIMD4 antibody (C-Term)

Catalog No. ABIN6990639

This anti-TIMD4 antibody is a Rabbit Polyclonal antibody detecting TIMD4 in ELISA and WB. Suitable for Human, Mouse and Rat.

Quick Overview for TIMD4 antibody (C-Term) (ABIN6990639)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMD4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-TIMD4 Antibody

Binding Specificity: C-Term

Purification: TIM-4 Antibody is affinity chromatography purified via peptide column.

Immunogen: TIM-4 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human TIM-4. The immunogen is located within the last 50 amino acids of TIM-4.

Isotype: IgG

Application Details

Application Notes: TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TIM-4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TIM-4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Alternative Name: TIM-4

Background: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Gene ID: 91937

NCBI Accession: NP_612388

UniProt: Q96H15

Pathways: Cancer Immune Checkpoints