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LGI3 antibody (AA 390-440)

LGI3 Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6990866
  • Target See all LGI3 Antibodies
    LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
    Binding Specificity
    • 15
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 390-440
    Reactivity
    • 19
    • 18
    • 13
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGI3 antibody is un-conjugated
    Application
    • 29
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Two isoforms of LGI3 are known to exist, this LGI3 antibody will recognize both. This LGI3 antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
    Purification
    LGI3 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    LGI3 antibody was raised against a 12 amino acid synthetic peptide from near the center of human LGI3. The immunogen is located within amino acids 390 - 440 of LGI3.
    Isotype
    IgG
    Top Product
    Discover our top product LGI3 Primary Antibody
  • Application Notes
    LGI3 antibody can be used for the detection of LGI3 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    LGI3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    LGI3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))
    Alternative Name
    LGI3 (LGI3 Products)
    Synonyms
    si:ch211-198o12.2 antibody, LGIL4 antibody, AI841179 antibody, AW049851 antibody, leucine rich repeat LGI family member 3 antibody, leucine-rich repeat LGI family, member 3 antibody, LGI3 antibody, lgi3 antibody, Lgi3 antibody
    Background
    LGI3 Antibody: The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.
    Gene ID
    203190
    UniProt
    Q8N145
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