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VGF antibody (C-Term)

The Rabbit Polyclonal anti-VGF antibody has been validated for WB, ELISA, IHC (p) and IF. It is suitable to detect VGF in samples from Human, Rat and Mouse.
Catalog No. ABIN6990908

Quick Overview for VGF antibody (C-Term) (ABIN6990908)

Target

See all VGF Antibodies
VGF (VGF Nerve Growth Factor Inducible (VGF))

Reactivity

  • 49
  • 33
  • 26
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Rat, Mouse

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VGF antibody is un-conjugated

Application

  • 50
  • 27
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  • 14
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  • 13
  • 12
  • 7
  • 4
  • 3
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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Binding Specificity

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    C-Term

    Purification

    VGF Antibody is affinity chromatography purified via peptide column.

    Immunogen

    VGF antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human VGF. The immunogen is located within the last 50 amino acids of VGF.

    Isotype

    IgG
  • Application Notes

    VGF antibody can be used for detection of VGF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    VGF Antibody is supplied in PBS containing 0.02 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,4 °C

    Storage Comment

    VGF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    VGF (VGF Nerve Growth Factor Inducible (VGF))

    Alternative Name

    VGF

    Background

    VGF Antibody: VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.

    Molecular Weight

    Predicted: 68 kDa

    Observed: 70 kDa 

    Gene ID

    7425

    NCBI Accession

    NP_003369

    UniProt

    O15240

    Pathways

    Hormone Transport, Carbohydrate Homeostasis
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