MED4 antibody (C-Term)
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- Target See all MED4 Antibodies
- MED4 (Mediator Complex Subunit 4 (MED4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MED4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- At least three isoforms of MED4 are known to exist, this antibody only recognizes the largest isoform.
- Purification
- MED4 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- MED4 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human MED4. The immunogen is located within the last 50 amino acids of MED4.
- Isotype
- IgG
- Top Product
- Discover our top product MED4 Primary Antibody
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- Application Notes
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MED4 antibody can be used for detection of MED4 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- MED4 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- MED4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- MED4 (Mediator Complex Subunit 4 (MED4))
- Alternative Name
- MED4 (MED4 Products)
- Synonyms
- zgc:110646 antibody, ARC36 antibody, DRIP36 antibody, HSPC126 antibody, TRAP36 antibody, VDRIP antibody, Vdrip antibody, 2410046H15Rik antibody, Vdirp antibody, mediator complex subunit 4 antibody, mediator complex subunit 4 S homeolog antibody, med4 antibody, med4.S antibody, MED4 antibody, Med4 antibody
- Background
- MED4 Antibody: The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment.
- Gene ID
- 29079
- NCBI Accession
- NP_054885
- UniProt
- Q9NPJ6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
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