SRPX2 antibody (N-Term)

Catalog No. ABIN6991221

Product Details anti-SRPX2 Antibody

Target: SRPX2 (Sushi-Repeat Containing Protein, X-Linked 2 (SRPX2))

Binding Specificity: N-Term

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRPX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: SRPX2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SRPX2 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SRPX2. The immunogen is located within the first 50 amino acids of SRPX2.

Isotype: IgG

Application Details

Application Notes: SRPX2 antibody can be used for detection of SRPX2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SRPX2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SRPX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SRPX2

Target: SRPX2 (Sushi-Repeat Containing Protein, X-Linked 2 (SRPX2))

Alternative Name: SRPX2 (SRPX2 Products)

Synonyms: BPP antibody, CBPS antibody, PMGX antibody, RESDX antibody, SRPUL antibody, 1110039C07Rik antibody, SRP antibody, RGD1562444 antibody, sushi repeat containing protein, X-linked 2 antibody, sushi-repeat-containing protein, X-linked 2 antibody, SRPX2 antibody, Srpx2 antibody

Background: SRPX2 Antibody: Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain, mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.

Gene ID: 27286

NCBI Accession: NP_055282

UniProt: O60687