SIRT5 antibody (C-Term)

Catalog No. ABIN6991346

The Chicken Polyclonal anti-SIRT5 antibody has been validated for WB and ELISA. It is suitable to detect SIRT5 in samples from Human and Mouse.

Quick Overview for SIRT5 antibody (C-Term) (ABIN6991346)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reactivity: Human, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRT5 Antibody

Binding Specificity: C-Term

Purification: SIRT5 Antibody is affinity chromatography purified via peptide column.

Immunogen: SIRT5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT5. The immunogen is located within the last 50 amino acids of SIRT5.

Isotype: IgY

Application Details

Application Notes: SIRT5 antibody can be used for detection of SIRT5 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIRT5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SIRT5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5

Background: SIRT5 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.

Gene ID: 23408

NCBI Accession: NP_036373

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interactome