EFCAB4A antibody (AA 290-340)

Catalog No. ABIN6991439

Product Details anti-EFCAB4A Antibody

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Binding Specificity: AA 290-340

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFCAB4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: EFCAB4A Antibody is affinity chromatography purified via peptide column.

Immunogen: EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A. The immunogen is located within amino acids 290 - 340 of EFCAB4A.

Isotype: IgG

Application Details

Application Notes: EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: EFCAB4A Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: EFCAB4A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for EFCAB4A

Target: EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))

Alternative Name: EFCAB4A (EFCAB4A Products)

Synonyms: CRACR2B antibody, 6330520A15Rik antibody, BC026645 antibody, Cracr2a antibody, Efcab4 antibody, RGD1560911 antibody, zgc:158448 antibody, calcium release activated channel regulator 2B antibody, cracr2b antibody, CRACR2B antibody, Cracr2b antibody

Background: EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.

Gene ID: 283229

NCBI Accession: NP_775855

UniProt: Q8N4Y2