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EFCAB4A antibody (Center)

EFCAB4A Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783783
  • Target See all EFCAB4A Antibodies
    EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))
    Binding Specificity
    • 1
    • 1
    • 1
    Center
    Reactivity
    Human, Mouse, Rat
    Host
    • 2
    • 1
    Rabbit
    Clonality
    • 2
    • 1
    Polyclonal
    Conjugate
    • 3
    This EFCAB4A antibody is un-conjugated
    Application
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects EFCAB4A at Center.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    15 amino acid peptide near the center of human EFCAB4A
    Top Product
    Discover our top product EFCAB4A Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    EFCAB4A (EF-Hand Calcium Binding Domain 4A (EFCAB4A))
    Alternative Name
    EFCAB4A (EFCAB4A Products)
    Synonyms
    CRACR2B antibody, 6330520A15Rik antibody, BC026645 antibody, Cracr2a antibody, Efcab4 antibody, RGD1560911 antibody, zgc:158448 antibody, calcium release activated channel regulator 2B antibody, cracr2b antibody, CRACR2B antibody, Cracr2b antibody
    Background
    EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.Synonyms: EF-hand calcium-binding domain-containing protein 4A
    Gene ID
    283229
    NCBI Accession
    NP_775855
    UniProt
    Q8N4Y2
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