SLC39A5 antibody (AA 330-380)

Catalog No. ABIN6991454

The Rabbit Polyclonal anti-SLC39A5 antibody is suitable to detect SLC39A5 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC (p) and IF.

Quick Overview for SLC39A5 antibody (AA 330-380) (ABIN6991454)

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SLC39A5 Antibody

Binding Specificity: AA 330-380

Purification: ZIP5 Antibody is affinity chromatography purified via peptide column.

Immunogen: ZIP5 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIP5. The immunogen is located within amino acids 330 - 380 of ZIP5.

Isotype: IgG

Application Details

Application Notes: ZIP5 antibody can be used for detection of ZIP5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIP5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZIP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SLC39A5

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Alternative Name: ZIP5

Background: ZIP5 Antibody: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

Gene ID: 283375

NCBI Accession: NP_001128667

UniProt: Q6ZMH5

Pathways: Transition Metal Ion Homeostasis