GDF1 antibody (N-Term)

Catalog No. ABIN6991778

Product Details anti-GDF1 Antibody

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Binding Specificity: AA 30-80, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family.

Purification: GDF1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal GDF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human GDF1. The immunogen is located within amino acids 30 - 80 of GDF1.

Isotype: IgG

Application Details

Application Notes: GDF1 antibody can be used for detection of GDF1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GDF1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GDF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GDF1

Target: GDF1 (Growth Differentiation Factor 1 (GDF1))

Alternative Name: GDF1 (GDF1 Products)

Synonyms: DORV antibody, DTGA3 antibody, AI385651 antibody, Gdf-1 antibody, growth differentiation factor 1 antibody, GDF1 antibody, Gdf1 antibody

Background: GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.

Molecular Weight: 41 kDa

Gene ID: 2657

NCBI Accession: NP_001483

UniProt: P27539