JAKMIP1 antibody (AA 260-310)

Catalog No. ABIN6991799

The Rabbit Polyclonal anti-JAKMIP1 antibody is suitable to detect JAKMIP1 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for JAKMIP1 antibody (AA 260-310) (ABIN6991799)

Target: JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAKMIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-JAKMIP1 Antibody

Binding Specificity: AA 260-310

Specificity: Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.

Purification: JAKMIP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.

Isotype: IgG

Application Details

Application Notes: JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: JAKMIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: JAKMIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for JAKMIP1

Target: JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))

Alternative Name: JAKMIP1

Background: JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.

Molecular Weight: Predicted: 69 kDa

Gene ID: 152789

NCBI Accession: NP_653321

UniProt: Q96N16

Pathways: SARS-CoV-2 Protein Interactome