PDGFB antibody (C-Term)

Catalog No. ABIN6991812

The Rabbit Polyclonal anti-PDGFB antibody (ABIN6991812) specifically detects PDGFB in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PDGFB antibody (C-Term) (ABIN6991812)

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-PDGFB Antibody

Binding Specificity: C-Term

Purification: PDGF-B Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal PDGF-B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PDGF-B. The immunogen is located within the last 50 amino acids of PDGF-B.

Isotype: IgG

Application Details

Application Notes: PDGF-B antibody can be used for detection of PDGF-B by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PDGF-B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PDGF-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PDGFB

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Alternative Name: PDGF-B

Background: PDGF-B Antibody: The platelet-derived growth factor beta (PDGF-B) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB). Mutations in this gene are associated with meningioma , and reciprocal translocations between chromosomes 22 and 7, at sites where the PDGF-B gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans.

Molecular Weight: Predicted: 27 kDa

Gene ID: 5155

NCBI Accession: NP_002599

UniProt: P01127

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling