GBP5 antibody (C-Term)

Catalog No. ABIN6991856

The Rabbit Polyclonal anti-GBP5 antibody is suitable to detect GBP5 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for GBP5 antibody (C-Term) (ABIN6991856)

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GBP5 Antibody

Binding Specificity: C-Term

Specificity: GBP5 antibody is predicted to not cross-react with other GBP family members.

Purification: GBP5 Antibody is affinity chromatography purified via peptide column.

Immunogen: GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 . The immunogen is located within the last 50 amino acids of GBP5.

Isotype: IgG

Application Details

Application Notes: GBP5 Antibody can be used for detection of GBP5 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: GBP5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: GBP5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for GBP5

Target: GBP5 (Guanylate Binding Protein 5 (GBP5))

Alternative Name: GBP5

Background: GBP5 Antibody: The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

Molecular Weight: Predicted: 64 kDa

Observed: 66 kDa

Gene ID: 115362

NCBI Accession: NP_443174

UniProt: Q96PP8