CEACAM5 antibody (AA 310-360)

Catalog No. ABIN6991895

The Rabbit Polyclonal anti-CEACAM5 antibody is suitable to detect CEACAM5 in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for CEACAM5 antibody (AA 310-360) (ABIN6991895)

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEACAM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CEACAM5 Antibody

Binding Specificity: AA 310-360

Specificity: CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.

Purification: CEACAM5 Antibody is affinity chromatography purified via peptide column.

Immunogen: CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5. The immunogen is located within amino acids 310 - 360 of CEACAM5 .

Isotype: IgG

Application Details

Application Notes: CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CEACAM5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CEACAM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for CEACAM5

Target: CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))

Alternative Name: CEACAM5

Background: CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).

Molecular Weight: Predicted: 77 kDa

Observed: 80kDa

Gene ID: 1048

NCBI Accession: NP_004354

UniProt: P06731