AMIGO1 antibody (C-Term)

Catalog No. ABIN6991930

This Rabbit Polyclonal antibody specifically detects AMIGO1 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AMIGO1 antibody (C-Term) (ABIN6991930)

Target: AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMIGO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AMIGO1 Antibody

Binding Specificity: C-Term

Specificity: AMIGO1 antibody is human, mouse, and rat reactive. AMIGO1 antibody is predicted to not cross-react with AMIGO2 or AMIGO3.

Purification: AMIGO1 antibody is affinity chromatography purified via peptide column.

Immunogen: AMIGO1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AMIGO1. The immunogen is located within the last 50 amino acids of AMIGO1.

Isotype: IgG

Application Details

Application Notes: AMIGO1 antibody can be used for detection of AMIGO1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: AMIGO1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: AMIGO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for AMIGO1

Target: AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))

Alternative Name: AMIGO1

Background: The amphoterin-induced gene and ORF (AMIGO1) protein is a brain-enriched, glycosylated transmembrane immunoglobulin (Ig) superfamily protein with six extracellular leucine-rich repeats (LRRs) and one Ig-like domain. It and the related proteins AMIGO2 and AMIGO3 are thought to be cell adhesion molecules expressed on fiber tracts of neuronal tissues and participate in their formation (1). AMIGO1 has also been suggested to play important roles in dendritic outgrowth during development and could modulate the survival of developing and adult neurons (2).

Molecular Weight: Predicted: 54 kDa

Observed: 55 kDa

Gene ID: 57463

NCBI Accession: NP_065754

UniProt: Q86WK6