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LC3C antibody (C-Term)

MAP1LC3C Reactivity: Human ELISA, WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991933
  • Target See all LC3C (MAP1LC3C) Antibodies
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    Binding Specificity
    • 15
    • 13
    • 9
    • 6
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 43
    • 3
    • 2
    Human
    Host
    • 41
    • 1
    • 1
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LC3C antibody is un-conjugated
    Application
    • 32
    • 26
    • 9
    • 7
    • 3
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    MAP1LC3C antibody is human, mouse and rat reactive. Multiple isoforms MAP1LC3C are known to exist. MAP1LC3C antibody is predicted to not cross-react with MAP1LC3A or MAP1LC3B.
    Purification
    MAP1LC3C antibody is affinity chromatography purified via peptide column.
    Immunogen
    MAP1LC3C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MAP1LC3C. The immunogen is located within the last 50 amino acids of MAP1LC3C.
    Isotype
    IgG
    Top Product
    Discover our top product MAP1LC3C Primary Antibody
  • Application Notes
    MAP1LC3C antibody can be used for detection of MAP1LC3C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    MAP1LC3C antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    MAP1LC3C antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    LC3C (MAP1LC3C) (Microtubule-Associated Protein 1 Light Chain 3 gamma (MAP1LC3C))
    Alternative Name
    MAP1LC3C (MAP1LC3C Products)
    Synonyms
    MAP1LC3C antibody, MGC154878 antibody, ATG8J antibody, LC3C antibody, microtubule associated protein 1 light chain 3 gamma antibody, microtubule associated protein 1 light chain 3 gamma L homeolog antibody, MAP1LC3C antibody, map1lc3c antibody, map1lc3c.L antibody
    Background
    Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and plasticity (1). MAP1LC3C belongs to the MAP1 LC3 family of proteins that form mature complexes with MAP1A and MAP1B which are thought to be important in the formation and development of axons and dendrites (2). MAP1LC3C is one of three isoforms of MAP1LC3, the mammalian homolog of yeast ATG8, an essential autophagy protein. These isoforms exhibit distinct expression patterns and MAP1LC3C, like MAP1LC3A but not MAP1LC3B, is post-translationally modified, suggesting the three isoforms may have different physiological functions (3).
    Molecular Weight
    Predicted: 16 kDa

    Observed: 16 kDa
    Gene ID
    440738
    NCBI Accession
    NP_001004343
    UniProt
    Q9BXW4
    Pathways
    Autophagy
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