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DOCK8 antibody (C-Term)

DOCK8 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6992016
  • Target See all DOCK8 Antibodies
    DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 5
    • 3
    Rabbit
    Clonality
    • 5
    • 3
    Polyclonal
    Conjugate
    • 8
    This DOCK8 antibody is un-conjugated
    Application
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.
    Purification
    DOCK8 antibody is affinity chromatography purified via peptide column.
    Immunogen
    DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8. The immunogen is located within the last 50 amino acids of DOCK8.
    Isotype
    IgG
    Top Product
    Discover our top product DOCK8 Primary Antibody
  • Application Notes
    DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    DOCK8 antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    DOCK8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))
    Alternative Name
    DOCK8 (DOCK8 Products)
    Synonyms
    im:7154406 antibody, si:dkey-91m11.1 antibody, MRD2 antibody, ZIR8 antibody, 1200017A24Rik antibody, 5830472H07Rik antibody, A130095G14Rik antibody, AI461977 antibody, dedicator of cytokinesis 8 antibody, dock8 antibody, DOCK8 antibody, Dock8 antibody
    Background
    The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).
    Molecular Weight
    Predicted: 166, 220, 231 kDa

    Observed: 220, 230 kDa
    Gene ID
    81704
    NCBI Accession
    NP_982272
    UniProt
    Q8NF50
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