DOCK8 antibody (AA 1-2099) (Biotin)

Catalog No. ABIN7984639

The Rabbit Polyclonal anti-DOCK8 antibody is suitable to detect DOCK8 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for DOCK8 antibody (AA 1-2099) (Biotin) (ABIN7984639)

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK8 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-DOCK8 Antibody (Biotin)

Binding Specificity: AA 1-2099

Purpose: Anti-DOCK8 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human DOCK8 shares 91.8% amino acid (aa) sequence identity with mouse DOCK8.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DOCK8 recombinant protein (Position: M1-S2099). Human DOCK8 shares 91.8% amino acid (aa) sequence identity with mouse DOCK8.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DOCK8

Target: DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))

Alternative Name: DOCK8

Background:

Background: This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Full Name: dedicator of cytokinesis 8

Gene ID: 81704

UniProt: Q8NF50