Phosducin-Like antibody (N-Term)

Catalog No. ABIN6992025

The Rabbit Polyclonal anti-Phosducin-Like antibody (ABIN6992025) specifically detects Phosducin-Like in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Phosducin-Like antibody (N-Term) (ABIN6992025)

Target: Phosducin-Like (PDCL)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phosducin-Like antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Phosducin-Like Antibody

Binding Specificity: N-Term

Specificity: PDCL antibody is human, mouse and rat reactive. At least two isoforms of PDCL are known to exist. PDCL antibody is predicted to not cross-react with other members of the PDCL protein family.

Purification: PDCL antibody is affinity chromatography purified via peptide column.

Immunogen: PDCL antibody was raised against a 16 amino acid peptide near the amino terminus of human PDCL. The immunogen is located within the first 50 amino acids of PDCL.

Isotype: IgG

Application Details

Application Notes: PDCL antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PDCL antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PDCL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for Phosducin-Like

Target: Phosducin-Like (PDCL)

Alternative Name: PDCL

Background: Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL is widely expressed in normal human tissues and may participate directly in the regulation of calcium-evoked exocytosis in adrenal medullary chromaffin cells (3). It is an ethanol-responsive modulator of heterotrimeric G proteins (4).

Molecular Weight: Predicted: 33 kDa

Observed: 35 kDa

Gene ID: 5082

NCBI Accession: NP_005379

UniProt: Q13371