RHOG antibody (N-Term)

Catalog No. ABIN6992068

Product Details anti-RHOG Antibody

Target: RHOG (Ras Homolog Family Member G (RHOG))

Binding Specificity: AA 40-90, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: RHOG antibody is human, mouse and rat reactive.

Purification: RHOG antibody is affinity chromatography purified via peptide column.

Immunogen: RHOG antibody was raised against a 15 amino acid peptide near the amino terminus of human RHOG. The immunogen is located within amino acids 40 - 90 of RHOG.

Isotype: IgG

Application Details

Application Notes: RHOG antibody can be used for detection of RHOG by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RHOG antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RHOG antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for RHOG

Target: RHOG (Ras Homolog Family Member G (RHOG))

Alternative Name: RHOG (RHOG Products)

Synonyms: 2810426G09Rik antibody, Arhg antibody, Sid10750 antibody, ARHG antibody, rhog antibody, zgc:55848 antibody, wu:fk30f01 antibody, arhg antibody, rhoga antibody, zgc:66008 antibody, ras homolog family member G antibody, ras homolog family member Gb antibody, ras homolog family member G S homeolog antibody, ras homolog gene family, member Gd antibody, Rhog antibody, rhogb antibody, RHOG antibody, rhog.S antibody, rhogd antibody

Background: The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3).

Molecular Weight: Predicted: 21 kDa

Observed: 23 kDa

Gene ID: 391

NCBI Accession: NP_001656

UniProt: P84095

Pathways: RTK Signaling