Angiotensin II antibody

Catalog No. ABIN7445423

This Rabbit Polyclonal antibody specifically detects Angiotensin II in IHC, WB, IP and ICC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Angiotensin II antibody (ABIN7445423)

Target: Angiotensin II (Ang II)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiotensin II antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Angiotensin II Antibody

Purpose: Polyclonal Antibody to Angiotensin II (AngII)

Specificity: The antibody is a rabbit polyclonal antibody raised against AngII. It has been selected for its ability to recognize AngII in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: OVA Conjugated Angiotensin II (AngII)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

References for anti-Angiotensin II antibody (ABIN7445423)

Zhang, Niu, Ren, Zhou, Yang, Yang, Wang, Luo, Shao, Zhang, Chen, Gao, Ge, Wu, Xiao: "Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model." in: Cells, Vol. 11, Issue 20, (2022) (PubMed).

Target Details for Angiotensin II

Target: Angiotensin II (Ang II)

Alternative Name: AngII

Background: Ang-II, Angiotensin-2

Pathways: JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity