Transportin 1 antibody (AA 626-836)

Catalog No. ABIN7431491

The Rabbit Polyclonal anti-Transportin 1 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect Transportin 1 in samples from Human.

Quick Overview for Transportin 1 antibody (AA 626-836) (ABIN7431491)

Target: Transportin 1 (TNPO1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Transportin 1 Antibody

Binding Specificity: AA 626-836

Purpose: Polyclonal Antibody to Transportin 1 (TNPO1)

Specificity: The antibody is a rabbit polyclonal antibody raised against TNPO1. It has been selected for its ability to recognize TNPO1 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Transportin 1 (TNPO1) corresdonding to Lys626~Val836 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.72 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for Transportin 1

Target: Transportin 1 (TNPO1)

Alternative Name: TNPO1

Background: MIP1, IPO2, KPNB2, MIP, MIP1, TRN, M9 region interaction protein 1, Importin 2, Karyopherin Beta 2

UniProt: Q92973

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events