ERBB3 antibody (AA 709-966)

Catalog No. ABIN7440770

The Rabbit Polyclonal anti-ERBB3 antibody has been validated for WB, IHC, IP and ICC. It is suitable to detect ERBB3 in samples from Human.

Quick Overview for ERBB3 antibody (AA 709-966) (ABIN7440770)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-ERBB3 Antibody

Binding Specificity: AA 709-966

Purpose: Polyclonal Antibody to V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3)

Specificity: The antibody is a rabbit polyclonal antibody raised against ErbB3. It has been selected for its ability to recognize ErbB3 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant V-Erb B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (ErbB3) corresdonding to Leu709~Thr966 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.32 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains ProClin and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: ErbB3

Background: HER3, MDA-BF-1, C-ErbB3, LCCS2, ErbB3-S, P180-ErbB3, P45-SErbB3, P85-SErbB3, Receptor Tyrosine-Protein Kinase ErbB-3, Lethal Congenital Contracture Syndrome 2

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway