BIM antibody (AA 2-120)

Catalog No. ABIN7430234

The Rabbit Polyclonal anti-BIM antibody has been validated for WB and IHC. It is suitable to detect BIM in samples from Human.

Quick Overview for BIM antibody (AA 2-120) (ABIN7430234)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BIM Antibody

Binding Specificity: AA 2-120

Purpose: Polyclonal Antibody to Bcl2 Like Protein 11 (BCL2L11)

Specificity: The antibody is a rabbit polyclonal antibody raised against BCL2L11. It has been selected for its ability to recognize BCL2L11 in immunohistochemical staining and western blotting.

Cross-Reactivity: Dog, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Bcl2 Like Protein 11 (BCL2L11) corresdonding to Ala2~Arg120 (Accession # O43521)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Alternative Name: BCL2L11

Background: BOD, BimL, BimEL, BIM, Bcl2-interacting mediator of cell death

UniProt: O43521

Pathways: PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity