JUP antibody

Catalog No. ABIN7237290

The Rabbit Polyclonal anti-JUP antibody has been validated for WB, IHC and ELISA. It is suitable to detect JUP in samples from Human, Mouse and Rat.

Quick Overview for JUP antibody (ABIN7237290)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-JUP Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human JUP

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: Catenin gamma

Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described.

Molecular Weight: 82 kDa

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location