PPP1R12A antibody
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- Target See all PPP1R12A Antibodies
- PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PPP1R12A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human PPP1R12A
- Isotype
- IgG
- Top Product
- Discover our top product PPP1R12A Primary Antibody
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- Application Notes
- WB 1:200-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.4 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))
- Alternative Name
- PPP1R12A (PPP1R12A Products)
- Background
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC.
- Molecular Weight
- 115 kDa
- UniProt
- O14974
- Pathways
- M Phase
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