LOX antibody
Quick Overview for LOX antibody (ABIN7000900)
Target
See all LOX AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Synthetic peptide of human LOX
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:25-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.3 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- LOX (Lysyl Oxidase (LOX))
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Alternative Name
- LOX
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Background
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 47 kDa
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NCBI Accession
- NP_002308
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UniProt
- P28300
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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