PTPRM antibody

Catalog No. ABIN7230846

The Rabbit Polyclonal anti-PTPRM antibody (ABIN7230846) specifically detects PTPRM in ELISA and WB. The antibody is reactive with Human and Mouse samples.

Quick Overview for PTPRM antibody (ABIN7230846)

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PTPRM Antibody

Purpose: PTPRM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PTPRM protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PTPRM protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM

Background: Rabbit Anti-PTPRM Polyclonal Antibody,Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu, R-PTP-mu,Protein Tyrosine Phosphatase, Receptor Type M encoded by PTPRM is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.,PTPRM

Molecular Weight: observerd band 159kDa

Gene ID: 5797

UniProt: P28827