TXN antibody

Catalog No. ABIN7238438

This Rabbit Polyclonal antibody specifically detects TXN in WB, IHC and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for TXN antibody (ABIN7238438)

Target: TXN (Thioredoxin (TXN))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TXN Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human TXN

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TXN

Target: TXN (Thioredoxin (TXN))

Alternative Name: TXN

Background: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity.

Molecular Weight: 12 kDa

NCBI Accession: NP_003320

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis