The Rabbit Polyclonal anti-Fibrinogen beta Chain antibody is suitable to detect Fibrinogen beta Chain in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.
FGB
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB 1:1000-1:5000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
Fibrinogen beta Chain (FGB)
Alternative Name
FGB
Background
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.