Cullin 4B antibody

Catalog No. ABIN7243220

The Rabbit Polyclonal anti-Cullin 4B antibody is suitable to detect Cullin 4B in samples from Human and Mouse. It has been validated for ELISA and IHC.

Quick Overview for Cullin 4B antibody (ABIN7243220)

Target: Cullin 4B (CUL4B)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Cullin 4B Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human CUL4B

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cullin 4B

Target: Cullin 4B (CUL4B)

Alternative Name: CUL4B

Background: This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_003579

UniProt: Q13620