PPARGC1B antibody

Catalog No. ABIN7243736

The Rabbit Polyclonal anti-PPARGC1B antibody (ABIN7243736) specifically detects PPARGC1B in ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for PPARGC1B antibody (ABIN7243736)

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPARGC1B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PPARGC1B Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human PPARGC1B

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPARGC1B

Target: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Alternative Name: PPARGC1B

Background: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

NCBI Accession: NP_001166169

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha