The Rabbit Polyclonal anti-PIK3CB antibody (ABIN7243745) specifically detects PIK3CB in IHC and ELISA.
The antibody is reactive with Human, Mouse and Rat samples.
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.