HMGA1 antibody
Quick Overview for HMGA1 antibody (ABIN7244237)
Target
See all HMGA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Synthetic peptide of human HMGA1
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Isotype
- IgG
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Application Notes
- IHC 1:50-200, ELISA 1:2000-10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HMGA1 (High Mobility Group AT-Hook 1 (HMGA1))
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Alternative Name
- HMGA1
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Background
- This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene.
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NCBI Accession
- NP_665906
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UniProt
- P17096
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Pathways
- Nuclear Hormone Receptor Binding, Autophagy
Target
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