MOSC1 antibody
Quick Overview for MOSC1 antibody (ABIN7244549)
Target
See all MOSC1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Synthetic peptide of human MARC1
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.5 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MOSC1 (MOCO Sulphurase C-terminal Domain Containing 1 (MOSC1))
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Alternative Name
- MARC1
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Background
- MOSC1 (MOCO sulphurase C-terminal domain containing 1), also known as MARC1, is a 337 amino acid mitochondrial protein that is thought to function as an oxidoreductase. Existing as three alternatively spliced isoforms, MOSC1 contains one MOSC domain and binds molybdenum as a cofactor. The gene encoding MOSC1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 37 kDa
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NCBI Accession
- NP_073583
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UniProt
- Q5VT66
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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