HLA-DRA antibody
Quick Overview for HLA-DRA antibody (ABIN7244882)
Target
See all HLA-DRA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human HLA-DRA
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Isotype
- IgG
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anti-HLA Class II DR alpha (HLA-DRA) (AA 26-254) antibody
HLA-DRA Reactivity: Human WB, FACS, ELISA, ICC Host: Mouse Monoclonal 1C11A5 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-216) antibodyHLA-DRA Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 27-216) antibodyHLA-DRA Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human, Rat, Mouse WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human IHC, FACS, IF, StM Host: Mouse Monoclonal 19-26-1-same as MB-26-1 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) antibodyHLA-DRA Reactivity: Human IHC Host: Rabbit Monoclonal MSVA-470R unconjugated Recombinant Antibody
anti-HLA Class II DR alpha (HLA-DRA) (AA 26-221) antibody (APC)HLA-DRA Reactivity: Rabbit WB, IHC Host: Guinea Pig Polyclonal APC
anti-HLA Class II DR alpha (HLA-DRA) (AA 149-177), (C-Term) antibodyHLA-DRA Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19527 unconjugated
anti-HLA Class II DR alpha (HLA-DRA) (AA 1-254) antibodyHLA-DRA Reactivity: Human WB Host: Mouse Polyclonal unconjugated
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Application Notes
- IHC 1:50-1:100, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.9 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HLA-DRA (HLA Class II DR alpha (HLA-DRA))
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Alternative Name
- HLA-DRA
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Background
- HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
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UniProt
- P01903
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Target
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