MRPL40 antibody (AA 60-140)

Catalog No. ABIN7221358

The Rabbit Polyclonal anti-MRPL40 antibody (ABIN7221358) specifically detects MRPL40 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for MRPL40 antibody (AA 60-140) (ABIN7221358)

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL40 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MRPL40 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-MRP-L22 Polyclonal Antibody

Specificity: MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human MRP-L22 at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL40

Target: MRPL40 (Mitochondrial Ribosomal Protein L40 (MRPL40))

Alternative Name: MRP-L22

Background: MRPL22, MRPL25, RPML25, HSPC158, 39S ribosomal protein L22, mitochondrial, L22mt, MRP-L22, 39S ribosomal protein L25, mitochondrial, L25mt, MRP-L25Mammalian mitochondrial ribosomal proteins are encoded by MRPL22 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to MRPL22 is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for MRPL22.

Molecular Weight: 24kD

Gene ID: 29093

UniProt: Q9NWU5