KCNJ10 antibody

Catalog No. ABIN7247834

This Rabbit Polyclonal antibody specifically detects KCNJ10 in IHC and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for KCNJ10 antibody (ABIN7247834)

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ10 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-KCNJ10 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human KCNJ10

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.08 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Alternative Name: KCNJ10

Background: KCNJ10 (Potassium Voltage-Gated Channel Subfamily J Member 10) is a Protein Coding gene. Diseases associated with KCNJ10 include Sesame Syndrome and Deafness, Autosomal Recessive 4, With Enlarged Vestibular Aqueduct. Among its related pathways are Inwardly rectifying K+ channels and GABA receptor activation. GO annotations related to this gene include identical protein binding and potassium channel activity. An important paralog of this gene is KCNJ15.This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.

UniProt: P78508

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity