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E-cadherin antibody

CDH1 Reactivity: Mouse, Rat IHC Host: Mouse Monoclonal EC125D unconjugated
Catalog No. ABIN7249790
  • Target See all E-cadherin (CDH1) Antibodies
    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
    Reactivity
    • 225
    • 83
    • 68
    • 18
    • 16
    • 12
    • 8
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 182
    • 78
    • 6
    • 4
    • 3
    Mouse
    Clonality
    • 166
    • 99
    • 4
    • 4
    Monoclonal
    Conjugate
    • 141
    • 30
    • 28
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This E-cadherin antibody is un-conjugated
    Application
    • 192
    • 94
    • 85
    • 67
    • 56
    • 54
    • 36
    • 33
    • 33
    • 27
    • 21
    • 16
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Characteristics
    Monoclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to MouseE-cadherin
    Clone
    EC125D
    Isotype
    IgG
    Top Product
    Discover our top product CDH1 Primary Antibody
  • Application Notes
    IHC 1:200-1:800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.6 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
    Alternative Name
    E-Cadherin (CDH1 Products)
    Background
    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
    UniProt
    P09803, Q9R0T4
    Pathways
    WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
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