Caspase 1 antibody (Cleaved-Asp210)
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- Target See all Caspase 1 (CASP1) Antibodies
- Caspase 1 (CASP1)
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Binding Specificity
- Cleaved-Asp210
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from the Internal region of human Caspase-1
- Isotype
- IgG
- Top Product
- Discover our top product CASP1 Primary Antibody
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anti-Caspase 1 (CASP1) (AA 317-404) antibody
CASP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 119-296) antibodyCASP1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-311) antibodyCASP1 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-100) antibodyCASP1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3D2 unconjugated
anti-Caspase 1 (CASP1) antibodyCASP1 Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 130-210), (Cleaved-Asp210) antibodyCASP1 Reactivity: Human WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-269) antibodyCASP1 Reactivity: Human IHC, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Caspase 1 (CASP1)
- Alternative Name
- CASP1 (CASP1 Products)
- Synonyms
- ICE antibody, IL1BC antibody, P45 antibody, Il1bc antibody, Ice antibody, CASP1 antibody, CG5370 antibody, DCP-1 antibody, DCP1 antibody, Dcp1 antibody, Dmel\\CG5370 antibody, ccp1 antibody, dcp-1 antibody, dcp1 antibody, l(2)01862 antibody, l(2)02132 antibody, caspase 1 antibody, caspase 1, apoptosis-related cysteine peptidase antibody, caspase 4, apoptosis-related cysteine peptidase antibody, Death caspase-1 antibody, caspase-1 antibody, caspase antibody, caspase recruitment domain-containing protein 16 antibody, caspase 4 antibody, CASP1 antibody, Casp1 antibody, CASP4 antibody, Dcp-1 antibody, Caspase1 antibody, LOC5564196 antibody, LOC451519 antibody
- Background
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
- Molecular Weight
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Observed_MW: 25 kDa
Calculated_MW: 45 kDa
- UniProt
- P29466
- Pathways
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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