MTAP antibody
Quick Overview for MTAP antibody (ABIN7252756)
Target
See all MTAP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human MTAP
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Isotype
- IgG
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Application Notes
- IHC 1:50-1:200, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.26 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- MTAP (Methylthioadenosine phosphorylase (MTAP))
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Alternative Name
- MTAP
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Background
- This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
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UniProt
- Q13126
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Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
Target
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