TSEN2 antibody

Catalog No. ABIN7253527

This Rabbit Polyclonal antibody specifically detects TSEN2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TSEN2 antibody (ABIN7253527)

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSEN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TSEN2 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TSEN2

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.44 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TSEN2

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Alternative Name: TSEN2

Background: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 53 kDa

UniProt: Q8NCE0

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha