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RAC2 antibody
RAC2
Reactivity: Human, Mouse
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RAC2 Antibody
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Target
See all RAC2 Antibodies
RAC2
(Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2))
Reactivity
All reactivities for RAC2 antibodies
Human, Mouse
Host
All hosts for RAC2 antibodies
Rabbit
Clonality
All clonalities for RAC2 antibodies
Polyclonal
Conjugate
All conjugates for RAC2 antibodies
This RAC2 antibody is un-conjugated
Application
All applications for RAC2 antibodies
ELISA, Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Antigen affinity purification
Immunogen
Synthetic peptide of human RAC2
Isotype
IgG
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Application Details
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Application Notes
IHC 1:50-1:200, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.02 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RAC2
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Target
RAC2
(Ras-Related C3 Botulinum Toxin Substrate 2 (Rho Family, Small GTP Binding Protein Rac2) (RAC2))
Alternative Name
RAC2 (RAC2 Products )
Synonyms
rac2 antibody, AI323801 antibody, AI452260 antibody, EN-7 antibody, Gx antibody, HSPC022 antibody, p21-Rac2 antibody, ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) antibody, RAS-related C3 botulinum substrate 2 antibody, Rac family small GTPase 2 antibody, rac2 antibody, Rac2 antibody, RAC2 antibody
Background
RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.
UniProt
P15153
Pathways
RTK Signaling , VEGF Signaling
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