Claudin 12 antibody
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- Target See all Claudin 12 (CLDN12) Antibodies
- Claudin 12 (CLDN12)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Claudin 12 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human CLDN12
- Isotype
- IgG
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- Application Notes
- IHC 1:30-1:150, ELISA 1:5000-1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.7 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Claudin 12 (CLDN12)
- Alternative Name
- CLDN12 (CLDN12 Products)
- Synonyms
- CLDN12 antibody, Claudin-12 antibody, DKFZp469F1620 antibody, zgc:86588 antibody, wu:fc27c11 antibody, wu:fc37h01 antibody, claudin-12 antibody, RGD1561053 antibody, claudin 12 antibody, claudin 12 S homeolog antibody, CLDN12 antibody, cldn12 antibody, Cldn12 antibody, cldn12.S antibody, CpipJ_CPIJ011954 antibody
- Background
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.
- UniProt
- P56749
- Pathways
- Cell-Cell Junction Organization