Claudin 12 antibody

Catalog No. ABIN7227940

This Rabbit Polyclonal antibody specifically detects Claudin 12 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Claudin 12 antibody (ABIN7227940)

Target: Claudin 12 (CLDN12)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Claudin 12 Antibody

Purpose: Rabbit Anti-CLD12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CLD12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CLD12 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Claudin 12

Target: Claudin 12 (CLDN12)

Alternative Name: CLD12

Background: Claudin-12CLDN12 (Claudin 12) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Blood-Brain Barrier and Immune Cell Transmigration: vCAM-1/CD106 Signaling Pathways. CLDN1 is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.

Molecular Weight: 26kD

Gene ID: 9069

UniProt: P56749

Pathways: Cell-Cell Junction Organization