SSRP1 antibody

Catalog No. ABIN7257250

Product Details anti-SSRP1 Antibody

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human SSRP1 (NP_003137.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Alternative Name: SSRP1 (SSRP1 Products)

Synonyms: ATHMG antibody, NFD antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antibody, SSRP1 antibody, high mobility group antibody, ssrp1 antibody, CG4817 antibody, Cf5 antibody, Dmel\\CG4817 antibody, DssRP antibody, SSRP antibody, dSSRP antibody, dSSRP1 antibody, dSsrp antibody, ssrp antibody, Ssrp1 antibody, DDBDRAFT_0188842 antibody, DDBDRAFT_0216434 antibody, DDB_0188842 antibody, DDB_0216434 antibody, wu:fa11b03 antibody, wu:fd10f06 antibody, FACT antibody, FACT80 antibody, T160 antibody, CIIDBP antibody, C81323 antibody, Hmg1-rs1 antibody, Hmgi-rs3 antibody, Hmgox antibody, high mobility group antibody, FACT complex subunit Ssrp1 antibody, FACT complex subunit SSRP1 antibody, Structure specific recognition protein antibody, structure specific recognition protein 1 antibody, transcription factor protein antibody, structure specific recognition protein 1a antibody, SSRP1 protein antibody, structure specific recognition protein 1 S homeolog antibody, HMG antibody, CpipJ_CPIJ002953 antibody, CpipJ_CPIJ020011 antibody, CMU_019430 antibody, Tsp_07406 antibody, LOC100286423 antibody, Ssrp antibody, ssrp1 antibody, SSRP1 antibody, ssrp1a antibody, nfd110 antibody, ssrp1.S antibody, Ssrp1 antibody

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.

Molecular Weight:

Observed_MW: 85 kDa

Calculated_MW: 81 kDa

Gene ID: 6749

UniProt: Q08945

Pathways: Chromatin Binding