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SSRP1 antibody (AA 1-242)

SSRP1 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7152517
  • Target See all SSRP1 Antibodies
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    Binding Specificity
    • 8
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242
    Reactivity
    • 59
    • 19
    • 16
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 55
    • 4
    Rabbit
    Clonality
    • 55
    • 4
    Polyclonal
    Conjugate
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SSRP1 antibody is un-conjugated
    Application
    • 42
    • 18
    • 10
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human FACT complex subunit SSRP1 protein (1-242AA)
    Isotype
    IgG
    Top Product
    Discover our top product SSRP1 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:2000-1:5000, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))
    Alternative Name
    SSRP1 (SSRP1 Products)
    Synonyms
    ATHMG antibody, NFD antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR D antibody, SSRP1 antibody, high mobility group antibody, ssrp1 antibody, CG4817 antibody, Cf5 antibody, Dmel\\CG4817 antibody, DssRP antibody, SSRP antibody, dSSRP antibody, dSSRP1 antibody, dSsrp antibody, ssrp antibody, Ssrp1 antibody, DDBDRAFT_0188842 antibody, DDBDRAFT_0216434 antibody, DDB_0188842 antibody, DDB_0216434 antibody, wu:fa11b03 antibody, wu:fd10f06 antibody, FACT antibody, FACT80 antibody, T160 antibody, CIIDBP antibody, C81323 antibody, Hmg1-rs1 antibody, Hmgi-rs3 antibody, Hmgox antibody, high mobility group antibody, FACT complex subunit Ssrp1 antibody, FACT complex subunit SSRP1 antibody, Structure specific recognition protein antibody, structure specific recognition protein 1 antibody, transcription factor protein antibody, structure specific recognition protein 1a antibody, SSRP1 protein antibody, structure specific recognition protein 1 S homeolog antibody, HMG antibody, CpipJ_CPIJ002953 antibody, CpipJ_CPIJ020011 antibody, CMU_019430 antibody, Tsp_07406 antibody, LOC100286423 antibody, Ssrp antibody, ssrp1 antibody, SSRP1 antibody, ssrp1a antibody, nfd110 antibody, ssrp1.S antibody, Ssrp1 antibody
    Background

    Background: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of \'Ser-392\' of p53/TP53 via its association with CK2 (casein kinase II). Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin. May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA. Also acts as a transcriptional coactivator for p63/TP63.

    Aliases: Chromatin-specific transcription elongation factor 80 kDa subunit antibody, Cisplatin DNA SSRP antibody, Facilitates chromatin remodeling 80 kDa subunit antibody, Facilitates chromatin transcription complex 80 kDa subunit antibody, Facilitates chromatin transcription complex subunit SSRP1 antibody, FACT 80 kDa subunit antibody, FACT complex subunit SSRP1 antibody, FACT80 antibody, FACTp80 antibody, hSSRP1 antibody, Recombination signal sequence recognition protein 1 antibody, Recombination signal sequence recognition protein antibody, SSRP 1 antibody, SSRP1 antibody, SSRP1_HUMAN antibody, Structure specific recognition protein 1 antibody, Structure-specific recognition protein 1 antibody, T160 antibody

    UniProt
    Q08945
    Pathways
    Chromatin Binding
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