MDFI antibody

Catalog No. ABIN7257327

This anti-MDFI antibody is a Rabbit Polyclonal antibody detecting MDFI in WB. Suitable for Rat and Mouse.

Quick Overview for MDFI antibody (ABIN7257327)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDFI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MDFI Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human MDFI (NP_005577.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Alternative Name: MDFI

Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Molecular Weight:

Observed_MW: 35 kDa

Calculated_MW: 25 kDa

Gene ID: 4188

UniProt: Q99750

Pathways: Maintenance of Protein Location