FREM1 antibody

Catalog No. ABIN7259276

The Rabbit Polyclonal anti-FREM1 antibody is suitable to detect FREM1 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for FREM1 antibody (ABIN7259276)

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FREM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FREM1 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human FREM1 (NP_659403.4).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FREM1

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Alternative Name: FREM1

Background: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

Molecular Weight:

Observed_MW: 72 kDa

Calculated_MW: 25 kDa/42 kDa/80 kDa/244 kDa

Gene ID: 158326

UniProt: Q5H8C1