FREM1 antibody (AA 1880-2179)

Catalog No. ABIN7267259

The Rabbit Polyclonal anti-FREM1 antibody is suitable to detect FREM1 in samples from Human. It has been validated for WB.

Quick Overview for FREM1 antibody (AA 1880-2179) (ABIN7267259)

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FREM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FREM1 Antibody

Binding Specificity: AA 1880-2179

Purpose: FREM1 Rabbit pAb

Sequence: GSSSSTTSGS FHLERRPLPS SMQLAVIRGD TLRGFDSTDL SQRKLRTRGN GKTVRPSSVY RNGTDIIYNY HGIVSLKLED DSFPTHKRKA KVSIISQPQK TIKVAELPQA DKVESTTDSH FPRQDQLPSF PKNCTLELKG LFHFEEGIQK LYQCNGIAWK AWSPQTKDVE DKSCPAGWHQ HSGYCHILIT EQKGTWNAAA QACREQYLGN LVTVFSRQHM RWLWDIGGRK SFWIGLNDQV HAGHWEWIGG EPVAFTNGRR GPSQRSKLGK SCVLVQRQGK WQTKDCRRAK PHNYVCSRKL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1880-2179 of human FREM1 (NP_659403.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FREM1

Target: FREM1 (FRAS1 Related Extracellular Matrix 1 (FREM1))

Alternative Name: FREM1

Background: This gene encodes a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon, the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.,FREM1,BNAR,C9orf143,C9orf145,C9orf154,MOTA,TILRR,TRIGNO2,Cell Biology & Developmental Biology,FREM1

Molecular Weight: 25kDa/42kDa/80kDa/244kDa

Gene ID: 158326

UniProt: Q5H8C1